
Nanofat Use in Regenerative Medicine: A Systematic Literature Review
ExAdEx-Innov contributes to Landmark Review on Nanofat in Regenerative Medicine We are delighted to announce the publication of our latest collaborative research with our partners
ExAdEx-Innov was delighted to participate in COSM’ING 2025, which took place from June 11 to 13, 2025, in Saint-Malo, France. This renowned congress, organized by Biotech Santé Bretagne, brought together leading experts from academia and industry to discuss the latest innovations in cosmetic ingredients and biotechnologies.
COSM’ING 2025 provided us an excellent opportunity to present both internal case studies and collaborative research on active ingredients, in partnership with Exsymol and Mibelle Biochemistry:
✨Cafeisilane® (with EXSYMOL Monaco): we showcased advanced analyses using confocal microscopy and SHG microscopy on our fibro-inflammatory tissue models for this silicium-caffeine complex. These studies highlighted the efficacy and mechanisms of action of Cafeisilane® in reducing cellulite in innovative and relevant tissue environments.
✨VividEye™ (with Mibelle Biochemistry): we presented 3D imaging and video-reconstruction analyses performed on our 3D vascularized tissue models for this apple mint-based ingredient. This work demonstrated new insights into the activity of VividEye™ in complex, physiologically relevant systems, for dark circles and puffy eyes.
Our human tissue models enabled the investigation of multiple mechanisms of action simultaneously, offering significant advantages over conventional models. This approach supports the development and repositioning of active ingredients on innovative scientific bases, providing real added value for the cosmetics industry.
WHEN: June 12-13, 2025
WHERE: Saint-Malo (France)
SESSION: NEW TOOLS & SERVICES
TITLE: Unique 3D Vascularized Donor Tissue Models for ex vivo mechanistic evaluation of dermo-cosmetic active ingredients
SPEAKER: Luigi Formicola, COO & Co-founder
ExAdEx-Innov contributes to Landmark Review on Nanofat in Regenerative Medicine We are delighted to announce the publication of our latest collaborative research with our partners
ExAdEx-Innov has been awarded the prestigious Descroix-Vernier EthicScience 2025 Award in the « Prix du Jury – Espoir de la Recherche » category for its work in
ExAdEx-Innov is set to showcase its most recent dermo-cosmetic research on its proprietary 3D vascularized adult tissue models at COMET Congress 2025 The COMET Congress,
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KOL on adipose tissue biology.
Research Director (DR1 INSERM).
Team Leader of « Stem Cells and Differentiation » Lab at Institut de Biologie Valrose (Nice).
Label of Laboratoire d’Excellence by the French National Research Agency (Investissements pour le Futur, Labex Signalife program).
Co-inventor of 5 patents
Expert in clinical applications of adipose tissue.
Plastic Reconstructive and Aesthetic Surgeon in Nice.
Member of the Medical Council of Alpes Maritimes region.
Expert for the French National Regulatory Agency ANSM for medical devices.
Certified by French Health Autority HAS (2020-2024).
PhD thesis (2018) on fat tissue and adipose tissue stem cells grafting.
Expert in cell therapy and immunology.
Senior Lecturer (Maitre de conférences).
Responsible of the Cell and Gene Therapy Unity of Nice University Hospital (CHU de Nice).
Director of « Micoralis » research team at Université Côte d’Azur (Nice).
Founder and CEO of the biotech company Biointerférence (2003-2006).
Co-inventor of 5 patents.
Vincent is responsible of company strategy and technological innovation, thanks to his double skill set in science and deeptech startup development.
With a deep knowledge and vision about ExAdEx technology, Vincent has actively worked as a deeptech entrepreneur to push further the development of breakthrough innovative products around human adipose tissue, which lead him to create ExAdEx-Inov.
In addition to his entrepreneurial skills, Vincent has a strong background in biology (PhD in Cellular and Molecular Biology from Université Côte d’Azur) and training in clinical research management (CRA training at the Faculty of Medicine of La Timone, Marseille).
He is co-inventor of the 2 company’s patent families.
Main areas of expertise: DeepTech entrepreneur; Bioengineering of human adipose tissue.
Luigi is responsible of the management of company operations and business development strategy, thanks to his expertise in biotech startup development.
With a double competence and training in business and science (including an MBA from IAE Paris Sorbonne Business School and a PhD in Cytological Sciences from Rome University La Sapienza), Luigi has been managing business development and R&D projects in a preclinical CRO and a biotech startup company in previous years.
He has been supporting ExAdEx-Innov project and business development since his position as an Entrepreneur in Residence for CNRS Innovation Tech Transfer Office in 2021.
Main areas of expertise: Biotech Startup Business Development; Project management