
GLP-1 agonists and Face Aging: Decoding Effects with Ex Vivo Facial Models
Understanding and countering facial tissue effects with our unique donor ex vivo models The rise of GLP-1 agonists is revolutionizing obesity management, but has revealing
ExAdEx‑Innov is proud to announce the launch of the Longevity Lab, a hybrid in‑silico / ex vivo platform designed to accelerate R&D in tissue longevity. Built on Human Tissue Intelligence, this new tool integrates 24 relevant endpoints of aging‑related biology and enables cosmetic, dermo‑cosmetic, and biotech teams to benchmark actives, formulations, and therapeutic strategies against a comprehensive panel of biomarkers.
Aging and Longevity are a Tissue StoryExAdEx Longevity Lab™ is our holistic approach to study aging and longevity in an ex vivo context. Unlike traditional approaches that isolate individual endpoints, ExAdEx Longevity Lab™ aims at longevity as a holistic phenomenon at the tissue level — investigating multiple processes occurring in aging, from limited extracellular matrix remodeling, stem cell pool exhaustion, mitochondrial dysfunction, vascular impairment and chronic inflammatory processes. Our advanced ex vivo systems coupled with a computed approach enable multi-parametric evaluation of active ingredients in a physiologically relevant context that goes beyond single-cell assays to true tissue homeostasis and rejuvenation stimulation.
What Is ExAdEx Longevity Lab™?ExAdEx Longevity Lab™ connects real human tissue data — generated from our ex vivo human subcutaneous tissue-derived models — with in‑silico analysis to deliver mechanistic, tissue‑relevant insights. From tissue regeneration and extracellular matrix remodeling to senescence, inflammaging, and metabolic signatures, the platform offers a structured way to explore how an ingredient or protocol influences key aspects of long‑term tissue health.
How can ExAdEx Longevity Lab™ support you?For R&D teams, ExAdEx Longevity Lab™ provides a powerful layer between screening and claim substantiation. By testing up to 24 endpoints of longevity in a single integrated framework, you can:
ExAdEx Longevity Lab™ bridges the gap between ex vivo research and in vivo outcomes, helping brands and developers unlock claims from real human tissues — not just from cell lines or synthetic assays alone.
Dive into ExAdEx Longevity Lab™ExAdEx Longevity Lab™ is now accessible online and can be used as a standalone exploratory tool or integrated with ExAdEx‑Innov’s custom services. Whether you are working on anti‑aging actives, regenerative strategies, or metabolic health‑related approaches in dermocosmetics, nutraceuticals and aesthetic medicine, our platform is designed to support your innovation pipeline from target identification to claim validation.

Understanding and countering facial tissue effects with our unique donor ex vivo models The rise of GLP-1 agonists is revolutionizing obesity management, but has revealing

ExAdEx-Innov contributes to a publication on adipose tissue processing ExAdEx-Innov is proud to contribute to a new collaborative study published in Scientific Reports, a journal

ExAdEx-Innov proudly contributed to the 19th International Symposium “Cosmetic Science: Shaping the Future” organized by the Société Française de Cosmétologie (SFC) in Paris on December
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KOL on adipose tissue biology.
Research Director (DR1 INSERM).
Team Leader of « Stem Cells and Differentiation » Lab at Institut de Biologie Valrose (Nice).
Label of Laboratoire d’Excellence by the French National Research Agency (Investissements pour le Futur, Labex Signalife program).
Co-inventor of 5 patents
Expert in clinical applications of adipose tissue.
Plastic Reconstructive and Aesthetic Surgeon in Nice.
Member of the Medical Council of Alpes Maritimes region.
Expert for the French National Regulatory Agency ANSM for medical devices.
Certified by French Health Autority HAS (2020-2024).
PhD thesis (2018) on fat tissue and adipose tissue stem cells grafting.
Expert in cell therapy and immunology.
Senior Lecturer (Maitre de conférences).
Responsible of the Cell and Gene Therapy Unity of Nice University Hospital (CHU de Nice).
Director of « Micoralis » research team at Université Côte d’Azur (Nice).
Founder and CEO of the biotech company Biointerférence (2003-2006).
Co-inventor of 5 patents.
Vincent is responsible of company strategy and technological innovation, thanks to his double skill set in science and deeptech startup development.
With a deep knowledge and vision about ExAdEx technology, Vincent has actively worked as a deeptech entrepreneur to push further the development of breakthrough innovative products around human adipose tissue, which lead him to create ExAdEx-Inov.
In addition to his entrepreneurial skills, Vincent has a strong background in biology (PhD in Cellular and Molecular Biology from Université Côte d’Azur) and training in clinical research management (CRA training at the Faculty of Medicine of La Timone, Marseille).
He is co-inventor of the 2 company’s patent families.
Main areas of expertise: DeepTech entrepreneur; Bioengineering of human adipose tissue.
Luigi is responsible of the management of company operations and business development strategy, thanks to his expertise in biotech startup development.
With a double competence and training in business and science (including an MBA from IAE Paris Sorbonne Business School and a PhD in Cytological Sciences from Rome University La Sapienza), Luigi has been managing business development and R&D projects in a preclinical CRO and a biotech startup company in previous years.
He has been supporting ExAdEx-Innov project and business development since his position as an Entrepreneur in Residence for CNRS Innovation Tech Transfer Office in 2021.
Main areas of expertise: Biotech Startup Business Development; Project management